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The SPAM category is based on patterns and a blocked senders list. If SPAM falls into this category it is deleted, and not delivered to your mailbox.
The SUSPECTED SPAM category is based on heuristics and as such is more likely to falsely identify legitimate mail as SPAM if it has certain words and characteristics (eg "make money fast"). Mail in this category will be tagged in the subject line with "[SUSPECTED SPAM] ", and delivered to your mailbox.
Our experience is that there will be a low volume in the SUSPECTED SPAM category, and that it is safer to deliver the mail in this case, rather than run the risk of losing legitimate mail.
It is important, however, to realise that the SPAM solution will not catch 100% of spam, and that while it has a very low false positive rate (mail that is not SPAM being detected as SPAM), there is still the chance of mail being falsely detected and deleted. (See also point 19 for general rules about reducing SPAM).